To carry out groundbreaking fundamental and clinical research to benefit children with cancer, infection, and immune-related disorders.
The faculty members of Center for Cancer and Immunology Research study the molecular and cellular basis for cancer, autoimmune, neurofibromatosis, and infectious diseases, and develop experimental therapies for children with these illnesses. Our investigators conduct high impact studies on brain cancer, immune regulation and stem cells, and the molecular pathogenesis of human immunodeficiency virus as it relates to pediatric AIDS. In addition to fundamental research, the center has a major emphasis on translational research. Our clinical investigators are leaders in multiple national and international consortiums of clinical trials. Research programs for experimental therapies are being developed for neurofibromatosis, medulloblastoma, sarcoma, leukemia, and lymphoma.
Children’s National has committed substantial resources to expand the center, as exemplified by substantial new recruitments, new research infrastructure, and newly renovated laboratory space. With an ongoing recruitment of seven new faculty members, the center now consists of both research and clinical investigators with expertise in cancer genetics, cancer and tissue stem cells, cancer host cell interaction, microbe-host interaction, inflammation, and immunotherapy. These areas are highly interrelated, allowing us to work collaboratively with related diseases models and research tools.